Table 2.
The HR and 95% CI from the Cox regression model of risk factors for hospitalised sickle cell disease records, 2012–2017
| Variables | HR | 95% CI | P value |
| Calendar-year (years) | 0.99 | 0.99 to 1.00 | 0.151 |
| Age group (years) | |||
| 0–4 | ref | ||
| 5–9 | 0.99 | 0.94 to 1.05 | 0.830 |
| 10–14 | 1.08 | 1.01 to 1.14 | 0.018 |
| 15–19 | 1.17 | 1.10 to 1.24 | <0.001 |
| 20–24 | 1.18 | 1.11 to 1.26 | <0.001 |
| 25–29 | 1.27 | 1.17 to 1.37 | <0.001 |
| 30–34 | 1.21 | 1.09 to 1.34 | <0.001 |
| 35–39 | 1.08 | 0.93 to 1.24 | 0.301 |
| 40–44 | 1.20 | 1.01 to 1.41 | 0.036 |
| 45–49 | 1.36 | 1.15 to 1.62 | <0.001 |
| 50–100 | 1.11 | 0.98 to 1.26 | 0.107 |
| Sex | |||
| Male | ref | ||
| Female | 1.03 | 0.98 to 1.10 | 0.259 |
| Region | |||
| Greater Accra | ref | ||
| Ashanti | 1.16 | 1.10 to 1.23 | <0.001 |
| Brong Ahafo | 0.96 | 0.92 to 1.01 | 0.099 |
| Central | 0.99 | 0.94 to 1.05 | 0.797 |
| Eastern | 0.93 | 0.89 to 0.97 | 0.001 |
| Northern | 0.91 | 0.85 to 0.98 | 0.017 |
| Upper East | 1.14 | 1.03 to 1.26 | 0.009 |
| Upper West | 1.14 | 1.03 to 1.28 | 0.016 |
| Volta | 0.92 | 0.88 to 0.96 | <0.001 |
| Western | 1.07 | 1.02 to 1.13 | 0.007 |
| Employment status | |||
| Unemployed | ref | ||
| Employed | 1.01 | 0.96 to 1.05 | 0.759 |
| Unspecified | 0.97 | 0.93 to 1.02 | 0.271 |
| Education level | |||
| No formal education | ref | ||
| Formal education | 1.01 | 0.98 to 1.04 | 0.523 |
| Health insurance ownership | |||
| No | ref | ||
| Yes | 0.98 | 0.95 to 1.02 | 0.366 |
| Surgical procedure on admission | |||
| No | ref | ||
| Yes | 0.78 | 0.69 to 0.87 | <0.001 |
| Comorbidity | |||
| No | ref | ||
| Yes | 0.88 | 0.86 to 0.90 | <0.001 |
| Age and sex interaction | |||
| 0–4 years#Female | ref | ||
| 5–9 years#Female | 1.02 | 0.94 to 1.11 | 0.568 |
| 10–14 years#Female | 0.99 | 0.91 to 1.08 | 0.894 |
| 15–19 years#Female | 1.03 | 0.95 to 1.12 | 0.406 |
| 20–24 years#Female | 0.96 | 0.88 to 1.05 | 0.396 |
| 25–29 years#Female | 0.88 | 0.80 to 0.98 | 0.017 |
| 30–34 years#Female | 0.90 | 0.79 to 1.03 | 0.116 |
| 35–39 years#Female | 0.96 | 0.81 to 1.14 | 0.653 |
| 40–44 years#Female | 0.93 | 0.76 to 1.14 | 0.489 |
| 45–49 years#Female | 0.88 | 0.70 to 1.10 | 0.251 |
| 50–100 years#Female | 0.89 | 0.76 to 1.04 | 0.148 |