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Examples of conjugation strategies and possible architectures: (a) grafting-to; (b) grafting-from, illustrated here as a peptide growing from a polymer backbone (polymer can also be grown from a peptide functionalized with an initiator or chain transfer agent); and (c) grafting-through methods. The left column shows conjugation reactions for generating comb/brush polymers, and the right column illustrates other possible architectures that can be realized by these methods.
