Figure 7.
AMP-polymer conjugate assemblies in aqueous solution: a) AMP-functionalized poly(acrylic acid)-block-polystyrene assembles into micelles with polystyrene cores, polyacrylic acid shells, and the AMP on the outermost surface, adapted with permission from Becker et al.,105 copyright © 2005 American Chemical Society; 105 b) comb polymer with pendant AMPs assembles into nanoparticles postulated to kill bacteria by membrane disruption, adapted with permission from Zhen et al.,111 copyright © 2019 Royal Society of Chemistry; and c) hyperbranched AMP-polymer conjugates form nanosheets that disrupt bacterial membranes, adapted with permission from Gao et al., copyright © 2016 American Chemical Society.56