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Zeta potential and selectivity of glucosamine-functionalized star polymers. In the schematic, red = polylysine, green = sugar-containing polymer, blue = neutral hydrophilic poly(hydroxylethylacrylamide). Adapted with permission from Wong et al.,113 copyright © 2016 American Chemical Society.
| |||
|---|---|---|---|
| PLL arm fraction (%) on conjugate |
Zeta potential (mV) |
MIC against S. aureus (μg/mL) |
Selectivity: IC50/MIC |
| 100 | 44.4 | 16-32 | ~0 |
| 75 | 33.6 | 32-64 | 7.0 |
| 50 | 33.4 | 64-128 | 3.8 |
| 35 | 23.2 | 256 | 2.4 |
