TABLE 3.
Coefficients from linear regression models predicting questionnaire variables [European Organization for Research and Treatment of Cancer Quality of Life Core (EORTC QLQ-C30) quality of life (QoL) scores, functional scores, and symptoms scales; Pittsburgh Sleep Quality Index (PSQI); Insomnia Severity Index (ISI); and Epworth Sleepiness Scale (ESS)].
| Variable | b | 95% CI | p |
| Quality of life (n = 79) | |||
| Sleep regularity index | 10.28 | 4.86 to 15.69 | < 0.001 |
| Gender: male | 31.73 | 10.49 to 52.97 | 0.0040 |
| Melanoma | –14.63 | −28.86 to −0.39 | 0.044 |
| Physical functioning (n = 80) | |||
| Sleep regularity index | 6.55 | 2.88 to 10.22 | < 0.001 |
| Age (years) | –4.57 | −7.78 to −1.36 | 0.0059 |
| Endometrial cancer | 12.30 | 4.81 to 19.78 | 0.0017 |
| Emotional functioning (n = 79) | |||
| Gender: male | 31.26 | 7.14 to 55.39 | 0.012 |
| Fatigue (n = 80) | |||
| Sleep regularity index | –7.50 | −12.76 to −2.24 | 0.0059 |
| Nausea/vomiting (n = 80) | |||
| Onset latency (log-transformed) | –3.63 | −7.21 to −0.04 | 0.048 |
| Sleep regularity index | –3.88 | −7.64 to −0.11 | 0.044 |
| Dyspnoea (n = 80) | |||
| Sleep regularity index | –5.53 | −10.92 to −0.13 | 0.045 |
| Insomnia (n = 80) | |||
| Gender: male | –37.01 | −70.28 to −3.75 | 0.030 |
| Appetite loss (n = 80) | |||
| Sleep time (h) | 4.55 | 0.16 to 8.94 | 0.042 |
| Constipation (n = 80) | |||
| Bed time | 5.89 | 0.87 to 10.91 | 0.022 |
| Diarrhea (n = 79) | |||
| Sleep time (h) | 2.97 | 0.25 to 5.69 | 0.033 |
| Onset latency (log-transformed) | –6.18 | −9.47 to −2.88 | < 0.001 |
| Sleep regularity index | –3.58 | −6.96 to −0.21 | 0.037 |
| Gender: male | –17.47 | −30.7 to −4.25 | 0.010 |
| Financial difficulties (n = 79) | |||
| Onset latency (log-transformed) | –8.93 | −15 to −2.86 | 0.0045 |
| Endometrial cancer | –16.50 | −29.21 to −3.8 | 0.012 |
| PSQI (n = 80) | |||
| Onset latency (log-transformed) | –1.14 | −2.19 to −0.08 | 0.035 |
| Sleep regularity index | –1.51 | −2.62 to −0.4 | 0.0082 |
| Endometrial cancer | –3.11 | −5.37 to −0.85 | 0.0076 |
| ISI (n = 80) | |||
| Sleep regularity index | –2.77 | −4.45 to −1.09 | 0.0016 |
| Gender: male | –6.90 | −13.49 to −0.31 | 0.041 |
| Endometrial cancer | –4.17 | −7.59 to −0.74 | 0.018 |
| ESS (n = 80) | |||
| Bedtime | –1.15 | −2.08 to −0.22 | 0.016 |
| Sleep regularity index | –2.86 | −3.96 to −1.76 | < 0.001 |
Only significant predictors are shown; for complete results, refer to Supplementary Tables 3–20. Numeric predictors were centered and scaled. Coefficients reflect the increase in scores for a one standard deviation increase in the predictor for continuous variables, or difference from the reference level for categorical variables, holding other variables constant.