Table 3:
Strongest Association Signals in the GENEVA Data. DMFT-associated genes, with top 10 ABT ranked p-values are reported. Underlined genes have been previously identified to be associated with dental caries. MIM numbers of genes not mentioned in the text: CSMD1 (MIM: 608397), RBFOX1 (MIM: 605104), and CLRN1 (MIM: 606397).
| Chr | Ensembl Gene | HGNC symbol | #SNP | p-value |
|---|---|---|---|---|
| 5 | ENSG00000248131 | CT49 | 20 | 7.717 × 10−6 |
| 8 | ENSG00000183117 | CSMD1 | 1659 | 2.328 × 10−5 |
| 16 | ENSG00000260411 | 713 | 5.491 × 10−5 | |
| 9 | ENSG00000153707 | PTPRD | 933 | 5.671 × 10−5 |
| 16 | ENSG00000078328 | RBFOX1 | 897 | 6.749 × 10−5 |
| 2 | ENSG00000230569 | 1 | 8.217 × 10−5 | |
| 8 | ENSG00000253317 | 3 | 1.303 × 10−4 | |
| 8 | ENSG00000215372 | ZNF705G | 1 | 1.755 × 10−4 |
| 3 | ENSG00000163646 | CLRN1 | 18 | 3.106 × 10−4 |
| 7 | ENSG00000214439 | FAM185BP | 14 | 3.608 × 10−4 |