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. Author manuscript; available in PMC: 2021 Oct 6.
Published in final edited form as: Chromosoma. 2019 Jun 29;128(3):369–383. doi: 10.1007/s00412-019-00713-9

Fig. 6. SIRT7 deficient oocytes have impaired chromosome synapsis.

Fig. 6

(a) Representative confocal images of pachytene and pachytene-like-staged oocytes immunostained with antibodies to detect HORMAD1 (gray) and SYCP3 (red) from wild-type (WT) and Sirt7−/− (KO) females at embryonic day 17.5. The box indicates the region of zoom. (b-c) Percentage of pachytene oocytes with HORMAD1-positive staining (b) and number of cells with the indicated number of asynaptic regions (c). Graph represents the mean ±SEM from 4 independent experiments (~90 oocytes per genotype). * P < 0.05; scale bars, 10μm and 2μm in the zoom.