Table 1.
Characteristics of the study population
| Size (n) | Age at blood draw mean ± SD (range) | Repeat size mean ± SD (range) | |
|---|---|---|---|
| Non-carriers | 55 | 50.03 ± 21.62 (16–85) | n/aa |
| Premutation carriers | 78 | 64.28 ± 14.29 (21–84) | 85.14 ± 19.5 (55–150) |
| Ataxia | 28 | 69.67 ± 8.18 (50–84) | 90.71 ± 18.82 (60–150) |
| No ataxia | 38 | 67.97 ± 9.29 (47–84) | 78.23 ± 16.99 (55–150) |
| Tremors | 52 | 66.85 ± 10.27 (23–84) | 86.33 ± 19.86 (55–150) |
| No tremors | 16 | 71.69 ± 9.78 (47–84) | 75.31 ± 9.13 (59–95) |
| Ataxia and tremors | 27 | 69.18 ± 7.89 (50–84) | 91.14 ± 19.04 (60–150) |
| No ataxia and tremors | 41 | 67.19 ± 11.64 (23–84) | 78.85 ± 16.56 (55–150) |
| Full mutation | 37 | 25.4 ± 10.39 (7–47) | > 200 |
a
We did not measure the repeat size due to the low frequency of FMR1 mutations in males in the general population