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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Adv Ther (Weinh). 2021 Jun 4;4(9):2100033. doi: 10.1002/adtp.202100033

Figure 7.

Figure 7.

A) Schematic illustration of the immunotherapy regimen: aPD-1 was injected on Day 1 and Day 5, and the mixture of pGM-CSF and TMB was co-injected into one tumor within the bilateral tumor model in mice, followed by ultrasound treatment on Day 4 and Day 8. Tumor growth and comparison of B) treated and C) distant tumors on Day 25. D) H&E staining in NTC, s-TMB + US and l-TMB + US treated tumor samples. IHC staining of Ki67 in E) treated and F) distant tumors. (Scale bars: 100 μm). *P < 0.05, **P < 0.01 and ##P < 0.01 vs. NTC. All data are plotted as mean ± SD.