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. 2021 Oct;31(10):1794–1806. doi: 10.1101/gr.272344.120

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© 2021 Erdmann-Pham et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see https://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 3. — Deconvolution biases for PBMC data with known ground-truth proportions. Average differences between inferred and true proportions were computed within each cell type across the 12 bulk samples present in each scenario. Consistent overestimation of a cell type's abundance results in darker blue squares, whereas red corresponds to chronic underestimation. Methods are ordered left to right by overall performance. (A) Deconvolution using Newman et al. (2019) data. (B) Deconvolution using Monaco et al. (2019) data.