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. 2021 Oct;31(10):1794–1806. doi: 10.1101/gr.272344.120

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© 2021 Erdmann-Pham et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see https://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 5. — RNA-Sieve results with confidence intervals in pseudobulk experiments. Inferred cell type proportions in pseudobulk experiments using data from the Tabula Muris Senis experiment for within-protocol (Smart-seq2 for both reference and pseudobulk) (A) and across-protocol (Smart-seq2 reference and 10x Chromium pseudobulk) (B) experiments. The black error bars on inferred proportions show the marginal 95% confidence intervals computed from the estimated Godambe information produced by RNA-Sieve. See “Confidence intervals” for mathematical details. Supplemental Table S2 contains the cell types in each organ, which could not be displayed because of space constraints.