Fig 1.

A. Detection thresholds for glucose [mM] and sucralose [μM] with and without Na-lactisole. There are two bar charts in Fig 1A. The chart on the left (blue) shows detection thresholds for glucose. The chart on the right (green) shows detection thresholds for sucralose. Each chart contains three bars. From left to right the bars are: 1) Threshold with no treatment, 2) Threshold with 2mM Na-lactisole, 3) Threshold with 2mM NaCl (to control for sodium present in lactisole). All treatments were paired with water rinses between stimuli. Twelve subjects participated in all conditions in duplicate. The error bars are standard errors of the mean. * indicates a significant difference p < .001. B. Impact of Na-lactisole on glucose and sucralose detection thresholds. The “fold increase” in threshold concentration is shown by taking the threshold concentration when treated with Na-lactisole and dividing it by the threshold concentration when untreated. The bar on the left (blue) represents glucose and the bar on the right (green) represents sucralose. The treatment concentration of Na-lactisole was 2 mM and the untreated condition contained the same level of sodium via the addition of 2 mM NaCl. All treatments were paired with water rinses between stimuli. Twelve subjects participated in all conditions in duplicate. The error bars are standard error of the mean. * indicates a significant difference, p < .05.