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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Curr Opin Gastroenterol. 2021 Sep 1;37(5):532–538. doi: 10.1097/MOG.0000000000000770

Table 1:

Risk factors for pancreatic cancer

Genetic mutations BRCA1, BRCA 2, CDKN2A/p16, ATM, PALB2, MLH1, MSH2, MSH6, PMS2, APC, STK11
Family history Individuals with at least two affected blood relatives on the same side of the family, of whom at least one is an FDR to the individual
Hereditary cancer syndromes Familial atypical multiple mole melanoma syndrome
Peutz Jeghers syndrome
Li Fraumeni syndrome
Lynch syndrome
Familial adenomatous polyposis
Other risk factors Chronic pancreatitis
Hereditary pancreatitis
New-onset diabetes mellitus
Obesity
Smoking
Alcohol