Table 1.

Details of the questions (except for the demographic information of the participants).

	Questions	Options
The non-pregnancy questionnaire covers a total of 35 questions
1	Which of the following indicators do you obtain when diagnosing hyperthyroidism? (Multiple choice)	fT3, fT4, tT3, tT4, TSH, thyroid ultrasound, RAIU, thyroid radionuclide scan
2	Which of the following indicators do you obtain when diagnosing GD? (Multiple choice)	TRAb, TPOAb, TgAb, peak flow velocity of the superior thyroid artery, invasive exophthalmos, anterior tibial mucinous edema
3	Do you ask hyperthyroid patients not to smoke?	Yes, no
4	Do you ask hyperthyroid patients not to expose themselves to secondhand smoke?	Yes, no
5	Do you ask hyperthyroid patients to take a low-iodine diet?	Yes, no
6	Do you ask hyperthyroid patients to use noniodized salt?	Yes, no
7	Which one do you think is the first-line treatment for hyperthyroidism?	MMI, PTU, RAI, thyroidectomy
8	How do you choose the initial dose of ATD?	MMI 30 mg or PTU 300 mg per day, according to the actual situation
9	(If you choose the second option in the previous question) Which one do you refer to for selecting the initial dose of ATD? (Multiple choice)	fT3 and fT4, fT3, TSH, age of the patient, results of hepatic function and the WBC count at baseline
10	How often is it recommended for patients to test their thyroid function during the initial period of ATD therapy?	Monthly, bimonthly, trimonthly
11	How often is it recommended for patients to test their thyroid function during the reduction period of ATD therapy?	Monthly, bimonthly, trimonthly
12	How often is it recommended for patients to test their thyroid function during the maintenance period of ATD therapy?	Monthly, bimonthly, trimonthly
13	Do you recommend that patients test their WBC count before ATD therapy?	Yes, No
14	How long is it recommended to test the WBC count after taking an ATD for the first time?	For 1 week, for 1–2 weeks, for 1 month, for 1–3 months, according to the side effects
15	How often is the WBC test recommended three months after an ATD is initiated?	Monthly, bimonthly, trimonthly, every 6 months, no recommendation
16	Do you recommend that patients test their baseline hepatic function?	Yes, No
17	Do you think hepatic function should be monitored during ATD treatment?	Yes, No
18	How often is the hepatic function test recommended during the first three months of ATD treatment?	Weekly, every 1–2 weeks, monthly, every 1–3 months, according to the side effects
19	How often is the hepatic function test recommended three months after an ATD is initiated?	Monthly, bimonthly, trimonthly, every 6 weeks, no recommendation, according to the side effects
20	Do you recommend taking hepatoprotective drugs for high alkaline phosphatase during the ATD treatment?	Yes, no
21	Do you recommend monitoring ANCA after PTU is applied?	Yes, no
22	Which of the following symptoms or signs will you pay attention to during ATD treatment? (Multiple choice)	Shown in Fig. 1
23	When would you consider withdrawing the ATD after initiation?	One year, 1.5 years, 2 years, according to the actual condition
24	Which of the following items would you use to estimate whether ATD treatment can be withdrawn? (Multiple choice)	TRAb returns to negative. Normal TSH. Normal fT4 or fT3. The dose of ATD to maintain normal TSH has been the lowest. The treatment course has reached 1.5 years. The goiter has shrunk to normal. Thyroid ultrasound indicates normal arterial blood flow.
25	How long do you recommend patients to be followed after withdrawing ATDs?	One month, 3months, 6 months, 1 year
26	Do you recommend the use of a compound iodine solution?	Yes, no
27	Which of the following would you choose to manage recurrence after withdrawing the ATD?	ATD, RAI, thyroidectomy
28	What is your preferred treatment for inactive GO?	ATD, RAI, thyroidectomy
29	What is your preferred treatment for active GO?	ATD, RAI, thyroidectomy
30	What is your preferred treatment for hepatic damage in hyperthyroid patients?	ATD, RAI, thyroidectomy
31	What is your preferred treatment when severe side effects of ATDs occur?	ATD, RAI, thyroidectomy
32	What is your preferred treatment for hyperthyroid patients with periodic paralysis?	ATD, RAI, thyroidectomy
33	What is your preferred treatment for hyperthyroid patients with TMNG?	ATD, RAI, thyroidectomy
34	What is your preferred treatment for hyperthyroid patients with TA?	ATD, RAI, thyroidectomy
35	What is your preferred treatment for elderly hyperthyroid patients with comorbidities?	ATD, RAI, thyroidectomy
The questions selected from the questionnaire on maternal thyroid diseases are listed below
1	Does your institution carry out prepregnancy thyroid disease screening?	Yes, no
2	Do you approve of the screening for thyroid diseases during pregnancy?	Yes, no
3	How do you carry out the screening for thyroid disease during pregnancy?	Among all pregnant women, among high-risk women
4	Has your institution established a pregnancy-specific reference interval for TSH?	Yes, no
5	Which medication would you recommend to hyperthyroid patients planning to become pregnant?	MMI, PTU
6	If you have applied MMI before pregnancy, which medication would you prefer during early pregnancy?	MMI, PTU
7	If you have applied PTU during T1, which medication would you prefer during T2, assuming an ATD is still required?	MMI, PTU
8	Do you recommend stopping the drug in T1 hyperthyroid patients, if an ATD was applied prior to pregnancy?	Yes, no

ATD, anti-thyroid drug; fT3, free triiodothyronine; fT4, free thyroxine; GD, Graves’ disease; GO, Graves’ ophthalmopathy; MMI, methimazole; PTU, propylthiouracil; RAI, radioactive iodine; RAIU, radioactive iodine uptake; T1, the first trimester; TA, toxic adenoma; TgAb, thyroglobulin antibody; TMNG, toxic multinodular goiter; TPOAb, thyroid peroxidase antibody; TRAb, thyrotropin receptor antibody; TSH, thyroid-stimulating hormone; tT3, total triiodothyronine; tT4, total thyroxine; WBC, white blood cell.