. 2021 Aug 23;10(9):1189–1199. doi: 10.1530/EC-21-0404
This work is licensed under a Table 1.
Basal and post-synacthen serum or salivary cortisol (F) and cortisone (E) levels. Data are expressed as means and s.e.
| Adrenal sufficient patients, n = 137 | Central AI, n = 37 | ||
|---|---|---|---|
| Normal HPA axis, n = 106 | RAS, n = 31 | ||
| Serum F0 (nmol/L) | 287.1 (9.7) | 265.4 (12.2) | 114.7 (15.1)a,b |
| Serum F30LDSST(nmol/L) | 512.4 (9.6) | 426.7 (13.4)a | 257.6 (24.3)a,b |
| Salivary F0 (nmol/L) | 5.82 (0.33) | 5.87 (0.48) | 2.26 (0.33)a,b |
| Salivary F30LDSST (nmol/L) | 31.16 (1.5) | 21.45 (1.45)a | 7.54 (1)a,b |
| Salivary E0 (nmol/L) | 28.7 (1.26) | 25.14 (1.62) | 12.85 (2.52)a,b |
| Salivary E30LDSST (nmol/L) | 63.63 (2.21) | 49.6 (3.2)a | 23.74 (2.92)a,b |
| Salivary F/E0 | 0.21 (0.01) | 0.24 (0.02) | 0.32 (0.07) |
| Salivary F/E30 | 0.5 (0.02) | 0.46 (0.04) | 0.44 (0.13) |
aP < 0.001 vs no treatment; bP < 0.001 vs stress dose.
AI, adrenal insufficiency; HPA, hypothalamic–pituitary–adrenal; RAS, relative adrenal sufficiency.