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. 2021 Sep 22;12:690619. doi: 10.3389/fphys.2021.690619

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Copyright © Rankovic, Draginic, Jeremic, Samanovic, Stojkov, Mitrovic, Jeremic, Radonjic, Srejovic, Bolevich, Svistunov, Jakovljevic and Turnic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in the heart tissue pro-oxidative parameters of O₂⁻ (A), hydrogen peroxide (H₂O₂; B), nitrites (NO₂⁻; C), and thiobarbituric acid (TBA) reactive substances (TBARS; D) in the control (CTRL), thiamine intraperitoneally (THIA), doxorubicin (DOX), and DOX+THIA groups. Values are presented as means±SEM. ^a p<0.05 compared with the normal CTRL group; ^b p<0.05 compared with the THIA group; ^c p<0.05 compared with the DOX group; and ^d p<0.05 compared with the DOX+THIA group.