Table 1.

Echocardiographic parameters of left ventricular function before and after treatment in all groups.

	Pre-treatment/At the beginning of experimental period
Groups	CTRL	DOX	THIA	DOX+THIA
Parameters
Ivsd (cm)	0.136±0.02	0.153±0.01	0.133±0.02	0.136±0.01
LviDd(cm)	0.390±0.01	0.475±0.01	0.390±0.02	0.423±0.05
LVPWd(cm)	0.157±0.02	0.162±0.02	0.151±0.02	0.157±0.01
IVSs(cm)	0.123±0.01	0.165±0.02	0.123±0.04	0.122±0.02
LVIDs(cm)	0.225±0.03	0.233±0.02	0.233±0.01	0.225±0.02
LVPWs(cm)	0.148±0.01	0.178±0.01	0.148±0.01	0.147±0.01
FS(%)	49.5±3.21	50.9±6.34	49.0±2.91	51.0±4.05
LVEDV	0.149±0.01	0.61±0.01	0.149±0.04	0.188±0.03
LVESV	0.030±0.01	0.034±0.03	0.034±0.01	0.030±0.03
EF(%)	79.59±2.76	87.11±5.33	77.40±3.22	83.82±9.71
	Post-treatment/At the end of experimental period
Groups	CTRL	DOX	THIA	DOX+THIA
Ivsd (cm)	0.199±0.02	0.174±0.02	0.174±0.02	0.191±0.02
LviDd(cm)	0.403±0.20	0.466±0.03	0.564±0.06	0.318±0.03
LVPWd(cm)	0.292±0.02	0.246±0.02	0.237±0.02	0.254±0.01
IVSs(cm)	0.191±0.03	0.186±0.02	0.199±0.01	0.169±0.01
LVIDs(cm)	0.182±0.01	0.288±0.05	0.275±0.01	0.159±0.01
LVPWs(cm)	0.258±0.02	0.258±0.02	0.220±0.01	0.135±0.01
FS(%)	54.7±5.76	38.2±6.29	51.1±3.32	46.7±2.26
	p =0.061	p =0.003	p =0.238	p =0.008
LVEDV	0.163±0.02	0.247±0.04	0.424±0.03	0.083±0.01
LVESV	0.016±0.02	0.062±0.04	0.054±0.04	0.011±0.01
EF(%)	90.00±8.34	74.83±9.88	87.16±8.02	86.72±4.87

Results are presented as mean±SEM. Statistical significance was determined by Repeat Measured ANOVA (RM-ANOVA). Statistical threshold of 0.05.