Fig. 6.

59-year-old women with history of LCIS with suspicious left breast calcifications on screening CEM. MLO low-energy image (A) and 2D ML magnification view (B) shows segmental fine pleomorphic calcifications in the lower breast (circle). MLO recombined image (C) demonstrates two enhancing masses (arrows) in the region of the calcifications and a superiorly located third mass (dashed arrow). Targeted US images (D) confirm three suspicious masses, two of which underwent US-guided biopsy yielding multicentric invasive ductal carcinoma. CEM may show greater extent of disease than conventional mammography, rendering more accurate staging.