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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Clin Imaging. 2020 Sep 19;69:269–279. doi: 10.1016/j.clinimag.2020.09.003

Table 3:

Evaluation of CEM in the Screening Setting

Study and Year No. of Women Modalities Compared Sensitivity (%) Specificity (%) PPV (%) NPV (%)
Jochelson et al, 2017 (52) 307 CEM vs MRI - 95 15 (of biopsy) -
94 14 (of biopsy)
Sorin et al, 2018 (53) 611 CEM vs CEM + US vs LE 91 76 12 100
91 61 8 99
52 91 16 98
Sung et al, 2019 (54) 904 CEM vs LE 88 94 21 100
50 97 25 99

Note.–CEM = contrast-enhanced mammography, LE = low-energy imaging, MRI = magnetic resonance imaging, NPV = negative predictive value, PPV = positive predictive value. US = ultrasound.