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Kinetic parameters for cleavage of ADAMTS-7 FRET substrate ATS7FP7 by ADAMTS-4, -5, and -7. Data are presented as average ± SEM; n = 3.
| Enzyme | kcat (s−1) | Km (μM) | kcat/ Km (M−1s−1) × 103 |
|---|---|---|---|
| ADAMTS-4 | 0.116 ± 0.0060 | 9.5 ± 1.7 | 13.4 ± 3.4 |
| ADAMTS-5 | 0.225 ± 0.042 | 81 ± 24 | 3.0 ± 0.44 |
| ADAMTS-7 | 0.035 ± 0.0017 | 10.5 ± 1.5 | 3.4 ± 0.36 |
