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. 2021 Oct 7;113:107946. doi: 10.1016/j.asoc.2021.107946

Table 1.

History of pandemics (sorted by death toll).

Name Time Deaths Frequency Mortality
Black Death (Bubonic Plague) 1347–1351 200 M 334 M  667 M 30%  60%
Smallpox 1520 56 M 187 M 30%
Spanish Flu 1918–1919 50 M 2000 M 2.5%
HIV/AIDS 1981–Present 32 M 1600 M 2%
Asian Flu 1957–1958 1.1 M 164 M 0.67%
Hong Kong Flu 1968–1970 1 M 200 M 0.5%
COVID-19 2019–Present (2020.6.3) 388 K 6.6 M 6%
Swine Flu 2009–2010 284 K 700 M 0.04%
Yellow Fever Late 1800s 60 K 170 K 35%
Ebola 2014–2016 11.3 K 23 K 50%
MERS 2012–Present 866 2519 35%
SARS 2002–2003 774 8098 9.5%

Center for Disease Control and Prevention (CDC), WHO, BBC, Wikipedia.