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. 2021 Sep 29;2021:5147069. doi: 10.1155/2021/5147069

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Copyright © 2021 Yilin Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Western blotting analysis of the effects of Nrf2 inhibitor ML385 or Nrf2 siRNA on Nrf2, HO-1, and NQO1 protein expression in the absence or presence of sesamin in normal and H/R-injured IEC-6 cells. (a) ML385 (10 μM) and (b) siRNA Nrf2 were used, respectively, to evaluate their relationships with sesamin (SE) (8 μM) in modulating H/R-injured IEC-6 cells (n = 3). Values are expressed as mean ± SEM. ^##P < 0.01 and ^###P < 0.001vs. the sham group; ^∗P < 0.05, ^∗∗P < 0.01, and ^∗∗∗P < 0.001vs. the H/R group; ^&&P < 0.01 and ^&&&P < 0.001vs. H/R and sesamin.