TABLE 3.
Antibiotic susceptibility of P. aeruginosa ATCC 27853 as a planktonic population (MIC) and as a biofilm population (MBEC) as derived by the NCCLS assay and an assay with the CBD
| Antibiotic | MIC (μg/ml)
|
MBEC (μg/ml)
|
||
|---|---|---|---|---|
| NCCLS assaya | Assay with CBDa | A650a | 0 CFU/pegb | |
| Amikacin | 2 | 4 | 16 | 16 |
| Aztreonam | 2 | 4 | >1,024 | >1,024 |
| Ceftazidime | 1 | 2 | >1,024 | >1,024 |
| Ciprofloxacin | 0.25 | 0.25 | 4 | 4 |
| Gentamicin | 2 | 4 | 128 | 128 |
| Imipenem | 1 | 4 | >1,024 | >1,024 |
| Piperacillin | 2 | 16 | >1,024 | >1,024 |
| Tobramycin | 0.5 | 1 | 2 | 2 |
a
The values were obtained by measuring the turbidity at 650 nm (A650) on a 96-well plate reader.
b
The values were obtained by determination of plate counts.