Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Oct 6;598(7879):159–166. doi: 10.1038/s41586-021-03970-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 5 — Related to Figs. 1, 2. Panels show brain-wide axonal projections (a–l) following injections of PHA-L (pink) into MOp-ul, AAV-RFP (red) and AAV-GFP (green) into immediately adjacent MOs and SSp-ul, respectively (injection sites shown in panel c). MOp-ul and SSp-ul project to similar cortical regions (a–e), however they differ in their projections to the thalamus and spinal cord, with SSp-ul uniquely innervating VPL (e, f) and targeting more dorsal layers of spinal cord (l), compared with MOp-ul. In addition, the MOs region just medial to MOp-ul is defined by prominent cortical projections to ORBvl (a, b), RSPd, and PTLp (f), and innervates MD and LP in thalamus (e, f), but lacks a projection to spinal cord (l). Together, these distinct projection profiles demonstrate differences in connectivity that emerge along the medial and lateral borders of MOp-ul. Acronyms are defined in Supplementary Table 1. Scale bars, 1 mm (left panels), 500 µm (right panels, a–l). Please see Supplementary Information for a detailed description of regional output from MOp-ul mapped using PHAL.