Extended Data Fig. 7. Signature Correspondence Between Developmental and Adult Samples.
a, Correlations were performed between the neuronal clusters in this dataset and the area specific identities calculated from adult human cortical areas as obtained from the Allen Institute Brain Map dataset. b, Module eigengene calculations of adult areal signatures show minimal to no correspondence to the signatures we identify in this study based upon low module eigengene values. n = 50,000 cells subsampled from full dataset. Mean with standard deviation error bars are shown. c, Module eigengene values of Allen excitatory neurons layer specific signatures in each of the developmental stages within our dataset. n = 50,000 cells subsampled from full dataset. Upper layer signatures emerge at late stages, while a small signal for deep layer identities can be observed at the earliest stages. Mean with standard deviation error bars are shown.