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. 2021 Oct 6;598(7879):195–199. doi: 10.1038/s41586-021-03969-3

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© The Author(s) 2021

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Extended Data Fig. 5 — a) Effect sizes for isoforms that split the L6 CT Grp_1 cluster into two parts is higher on average than that for genes. b) The App-205 isoform splits the L6 CT Grp_1 cluster into two parts where one part has a higher expression of the isoform whereas both halves have similar App gene expression. The white circles within the violin plots represent the mean and the white bars represent ±one standard deviation. c) Each point is a cell and is painted by the log1p(TPM) expression of the App gene (left) and App-205 isoform (middle). K-means clustering splits the L6 CT Grp_1 cluster into two distinct halves marked by expression of App-205. The white circles within the violin plots represent the mean and the white bars represent ±one standard deviation.