Table 5.
Multivariate regression analysis predicting the effect of a risk factor to AKI (n=2025)
| Factor | AOR | 95% CI | P value§ |
|---|---|---|---|
| Low Birth weight | 0.858 | 0.607–1.214 | 0.387 |
| Maternal medication | |||
| Vancomycin | 1.637 | 1.175–2.280 | 0.004** |
| Ceftazidime | 0.866 | 0.549–1.366 | 0.522237 |
| Amphotericin B | 1.302 | 0.702–2.416 | 0.402 |
| Loop diuretics | 2.203 | 1.565–3.101 | < 0.001** |
| NSAIDs | 1.403 | 0.882–2.231 | 0.153 |
| Central Line | 1.116 | 0.783–1.589 | 0.544 |
| Umbilical atrial catheter | 1.062 | 0.700–1.612 | 0.777 |
| Necrotizing enterocolitis | 1.039 | 0.633–1.708 | 0.879 |
| Patent ductus arteriosus | 1.009 | 0.708–1.437 | 0.962 |
| Respiratory distress syndrome | 1.067 | 0.729–1.561 | 0.739 |
| Intraventricular hemorrhage | 2.605 | 1.465–4.631 | 0.001** |
| Surgical intervention | 1.566 | 1.124–2.183 | 0.008** |
| Mechanical ventilation | 1.463 | 1.076–1.987 | 0.015** |
| Positive sepsis | 1.041 | 0.730–1.484 | 0.825 |
| Epinephrine | 1.416 | 0.866–2.314 | 0.165 |
| Dopamine | 2.399 | 1.676–3.435 | < 0.001** |
| Caffeine at GA < 29 weeks | 0.909 | 0.611–1.353 | 0.639 |
| Hypertension | 0.776 | 0.508–1.186 | 0.241 |
| Steroids | 0.780 | 0.558–1.090 | 0.145 |
| gestational age | 1.112 | 0.747–1.656 | 0.600 |
AKI Acute Kidney Injury; NSAIDs Non-steroidal anti-inflammatory drugs; GA-Gestational age; AOR Adjusted Odds Ratio
Crude Odds Ratio is presented for Mortality rates and extended length of Hospital Stay. Odds ratios were adjusted in the model such as; mortality, Extended LOS, birth weight, vancomycin, ceftazidime, amphotericin B, loop diuretics, NSAIDs, central line, umbilical atrial catheter, hypertension, Necrotizing Enterocolitis, Patent Ductus Arteriosus, Respiratory Distress Syndrome, Intraventricular Hemorrhage, Surgical Intervention, Mechanical Ventilation, Positive Sepsis, Epinephrine, Dopamine, Caffeine, hypertension, steroids, and gestational age
**Significant at P < 0.05 level