Table 1.
Baseline characteristics of the UKCS patients
| Variable | Total-89 |
|---|---|
| Age, years | 59 (53–69) |
| Gender, female | 54 (60.6%) |
| Ethnicity, Caucasian | 84 (94.4%) |
| Body mass index, (Kg/m2) | 31 (25–38) |
| Renal status at diagnosis | |
| Non-dialysis chronic kidney disease | 11 (12.4%) |
| Haemodialysis | 62 (69.6%) |
| Peritoneal dialysis | 16 (18.0%) |
| Co-morbidities | |
| Ischaemic heart disease | 35 (39.3%) |
| Myocardial infarction | 20 (22.5%) |
| Cerebrovascular disease | 12 (13.5%) |
| Peripheral vascular disease | 14 (15.7%) |
| Diabetes mellitus | 48 (53.9%) |
| Bone fractures | 2 (2.25%) |
| Hypertension | 58 (65.2%) |
| Parathyroidectomy | 8 (8.9%) |
| Medications | |
| Vitamin D analogues | 40 (44.9%) |
| Calcium based phosphate binders | 14 (15.7%) |
| Calcimimetics | 17 (19.1%) |
| Vitamin K antagonist (warfarin) | 24 (26.9%) |
| Distribution of skin lesions | |
| Abdomen | 24 (26.9%) |
| Breast | 6 (6.7%) |
| Lower extremities (leg/calf/toes) | 43 (48.3%) |
| Thighs | 22 (24.7%) |
| Buttock | 8 (9%) |
| Groins/genitalia | 4 (4.5%) |
| Hands and fingers | 6 (6.7%) |
| Laboratory results | |
| Haemoglobin, g/L | 94 (82–111) |
| Albumin, g/L | 27 (22–35) |
| Corrected calcium, mmol/L | 2.39 (2.24–2.53) |
| Phosphate, mmol/L | 1.66 (1.13–2.01) |
| Alkaline phosphatase, units/L | 157 (104–269) |
| Parathyroid hormonea, ng/L | 329.5 (78–679) |
| C-reactive proteinb, mg/L | 65 (14–145) |
Categorical variables expressed as number (percentage) and continuous variables expressed as median (interquartile range)
UKCS United Kingdom calciphylaxis study
aMissing Parathyroid hormone levels in 32 patients
bMissing CRP in 7 patients