Table 1.
Study demographics and pulmonary haemodynamics
| All | Alive | Dead | P-value* | |
|---|---|---|---|---|
| N | 116 | 55 | 61 | |
| Age (yrs) | 73 ± 7 | 71 ± 8 | 75 ± 7 | 0.018 |
| Gender (Male) | 50 (43%) | 15 (27%) | 35 (57%) | 0.001 |
| BMI (kg/m2) | 31 ± 6 | 31 ± 7 | 30 ± 6 | 0.284 |
| Heart rate (bpm) | 65 ± 12 | 65 ± 13 | 65 ± 11 | 0.800 |
| Diabetes mellitus | 30 (26%) | 13 (24%) | 17 (28%) | 0.607 |
| Hypercholesterolaemia | 24 (21%) | 11 (20%) | 13 (21%) | 0.863 |
| Hypertension | 78 (67%) | 41 (75%) | 37 (61%) | 0.056 |
| IHD | 20 (17%) | 9 (16%) | 11 (18%) | 0.814 |
| Atrial fibrillation | 82 (71%) | 32 (58%) | 50 (82%) | 0.009 |
| Stroke | 8 (7%) | 3 (5%) | 5 (8%) | 0.565 |
| Invasive haemodynamics | ||||
| Mean RA (mmHg) | 15 ± 5 | 14 ± 5 | 17 ± 5 | 0.004 |
| Mean PAP (mmHg) | 42 ± 10 | 39 ± 9 | 45 ± 10 | 0.002 |
| PCWP (mmHg) | 23 ± 5 | 23 ± 5 | 22 ± 5 | 0.327 |
| DPG (mmHg) | 1 ± 7 | -1 ± 6 | 3 ± 7 | < 0.001 |
| TPG (mmHg) | 19 ± 9 | 16 ± 7 | 22 ± 9 | < 0.001 |
| Cardiac index (L/min/m2) | 2.8 ± 1 | 2.9 ± 1.1 | 2.7 ± 0.8 | 0.432 |
| PVR (Wood unit) | 4.2 ± 2.95 | 3.16 ± 1.7 | 5 ± 3.5 | < 0.001 |
| O2 saturation (arterial) | 95 ± 4 | 95 ± 3 | 94 ± 4 | 0.071 |
| O2 saturation (venous) | 65 ± 9 | 68 ± 8 | 63 ± 10 | 0.005 |
Categorical comparisons done by Chi-square test
BMI Body mass index, IHD Ischaemic heart disease, RA right atrial, PAP pulmonary artery pressure, PCWP pulmonary capillary wedge pressure, DPG diastolic pulmonary gradient, TPG transpulmonary pressure gradient, PVR pulmonary vascular resistance
*P-value is for T-Test comparison between Alive and Dead cohorts