Fig. 1.

Sodium bicarbonate increased plasma bicarbonate and urinary sodium excretion and lowered urinary ammonium excretion, whereas sodium chloride treatment only increased urinary sodium excretion after 2 weeks of treatment. The horizontal black lines represent the median value; the lower and upper boundaries of the box represent the 25th and 75th percentiles; the whiskers represent the lowest and highest values. HCO₃⁻ bicarbonate, K⁺ potassium, Na⁺, sodium, NaCl sodium chloride, NH₄⁺ ammonium, NaHCO₃ sodium bicarbonate. *P < 0.05 for the within-group difference from baseline. ^†P = 0.07 for the within-group difference versus baseline; ^#P < 0.05 for the difference versus control