Table 2.

Blood pressure reduction and creatinine variation between groups

		eGFR < 45 mL/min n = 21 (52.5%)		eGFR ≥ 45 mL/min n = 19 (47.5%)		p value
Efficacy primary endpoint
Office BP reduction (SBP/DBP mmHg)	12-month FU	n = 12	− 19.42/− 9.50 ± 31.57/17.08	n = 13	− 19.92/1.38 ± 23.59/14.99	p = 0.998/p = 0.762
24-h ABPM reduction (mmHg)	12-month FU	n = 8	− 18.00/− 3.87  ± 23.4/11.93	n = 8	− 9.75/− 0.25 ± 24.58/14.27	p = 0.407/p = 0.764
Creatinine variation	3-month FU	n = 10	− 0.14 ± 0.27	n = 11	0.06 ± 0.18	p = 0.059
Creatinine variation	6-month FU	n = 13	− 0.10 ± 0.40	n = 10	0.01 ± 0.12	p = 0.374
Creatinine variation	12-month FU	n = 12	− 0.09 ± 0.75	n = 11	0.11 ± 0.28	p = 0.410