Table 4.
Results from morphometric OCT analysis
| Whole cohort | STEMI subgroup | |||||
|---|---|---|---|---|---|---|
| BRS | EES | P-value | BRS | EES | P-value | |
| Patient-level measurements | ||||||
| Patients, n | 70 | 32 | 60 | 24 | ||
| Stented length, mm | 19.8 (13.5, 24.5) | 21.7 (16.6, 26.6) | 0.77 | 19.25 (13.47, 23.85) | 21.7 (16.92, 27.5) | 0.53 |
| Reference lumen diameter, mm | 3.25 (2.81, 3.70) | 3.11 (2.73, 3.46) | 0.31 | 3.3 (2.83, 3.77) | 2.98 (2.73, 3.36) | 0.09 |
| Reference lumen area, mm2 | 8.38 (6.33, 10.88) | 7.65 (5.80, 9.44) | 0.22 | 8.60 (6.35, 11.19) | 7.02 (5.80, 8.86) | 0.04 |
| Minimum lumen diameter, mm | 2.56 (2.24, 2.92) | 2.50 (2.21, 2.98) | 0.97 | 2.53 (2.24, 2.85) | 2.47 (2.21, 2.82) | 0.58 |
| Maximum lumen diameter, mm | 3.26 (2.92, 3.86) | 3.28 (2.87, 3.75) | 0.64 | 3.22 (2.92, 3.80) | 3.2 (2.87, 3.73) | 0.40 |
| Minimum lumen area, mm2 | 5.13 (3.95, 6.70) | 4.93 (3.84, 6.99) | 0.96 | 5.04 (3.94, 6.84) | 4.79 (3.84, 6.26) | 0.49 |
| Maximum lumen area, mm2 | 8.35 (6.70, 11.71) | 8.49 (6.46, 11.03) | 0.59 | 8.17 (6.67, 11.34) | 8.05 (6.46, 10.95) | 0.32 |
| Minimum stent diameter, mm | 2.71 (2.47, 3.06) | 2.88 (2.46, 3.09) | 0.52 | 2.69 (2.46, 3.14) | 2.88 (2.46, 3.09) | 0.65 |
| Maximum stent diameter, mm | 3.29 (2.90, 3.78) | 3.29 (2.89, 3.59) | 0.40 | 3.27 (2.89, 3.67) | 3.26 (2.89, 3.59) | 0.50 |
| Minimum stent area, mm2 | 5.78 (4.88, 7.34) | 6.39 (4.77, 7.45) | 0.73 | 5.70 (4.83, 7.72) | 6.19 (4.77, 7.32) | 0.95 |
| Maximum stent area, mm2 | 8.52 (6.67, 11.25) | 8.50 (6.53, 10.14) | 0.30 | 8.41 (6.64, 10.57) | 8.36 (6.53, 10.14) | 0.37 |
| Minimum neointimal area, mm2 | -0.41 (-1.02, -0.01) | -0.23 (-0.63, 0.09) | 0.78 | -0.415 (-1.05, 0.01) | -0.20 (-0.63, 0.14) | 0.24 |
| Maximum neointimal area, mm2 | 1.09 (0.71, 1.75) | 1.30 (0.73, 1.57) | 0.49 | 1.01 (0.70, 1.49) | 1.35 (0.98, 1.70) | 0.16 |
| Stent/scaffold expansion index | 0.75 (0.64, 0.83) | 0.81 (0.71, 0.90) | 0.05 | 0.74 (0.64, 0.82) | 0.81 (0.71, 0.90) | 0.01 |
| Frame-level measurements | ||||||
| Assessed frames, n | 1,529 | 708 | 1,268 | 528 | ||
| Lumen diameter, mm | 2.91 (2.58, 3.34) | 2.94 (2.56, 3.31) | 0.84 | 2.88 (2.58, 3.35) | 2.83 (2.54, 3.23) | 0.61 |
| Lumen area, mm2 | 6.64 (5.23, 8.74) | 6.79 (5.15, 8.63) | 0.76 | 6.52 (5.22, 8.83) | 6.30 (5.07, 8.21) | 0.53 |
| Stent diameter, mm | 3.02 (2.69, 3.42) | 3.10 (2.70, 3.40) | 0.89 | 2.99 (2.68, 3.42) | 3.04 (2.67, 3.36) | 0.83 |
| Stent area, mm2 | 7.13 (5.69, 9.16) | 7.57 (5.73, 9.06) | 0.83 | 7.00 (5.64, 9.19) | 7.26 (5.61, 8.86) | 0.77 |
| Neointimal area, mm2 | 0.41 (0.10, 0.77) | 0.43 (0.15, 0.77) | 0.73 | 0.40 (0.09, 0.72) | 0.49 (0.19, 0.86) | 0.17 |
| Percentage area stenosis, % | 6.15 (1.27, 11.22) | 5.95 (2.06, 12.16) | 0.77 | 5.75 (1.18, 10.84) | 7.43 (2.43, 13.13) | 0.20 |
| Strut-level measurements | ||||||
| Visible struts, n | 12,704 | 7,123 | 10,527 | 5,236 | ||
| Covered struts, % | 97.5 | 90.9 | < 0.001 | 97.4 | 91.5 | < 0.001 |
| Uncovered struts, % | 1.3 | 7.5 | < 0.001 | 1.4 | 7.0 | < 0.001 |
| Malapposed struts, % | 0.5 | 1.1 | 0.51 | 0.5 | 0.9 | 0.58 |
| Non-apposed side branch struts, % | 0.7 | 0.5 | 0.56 | 0.7 | 0.6 | 0.61 |
| Neointimal coverage, µm | 85.5 (61.9, 124.1) | 69.5 (32.7, 127.5) | 0.20 | 82.7 (60.5, 118.8) | 76.6 (36.2, 139.5) | 0.84 |
Data shown as numbers, percentages or median (IQR)