Table 1.
Summary of the RVGRS950 and RVGRS950LDLR− distributions in the UK Biobank validation population.
| UK Biobank CAD cases | UK Biobank CAD-free controls | |
|---|---|---|
| Overall population | ||
| n | 3843 | 42,007 |
| RVGRS950 mean (SD) | 0.039 (0.69) | −0.009 (0.67) |
| RVGRS950LDLR- mean (SD) | 0.033 (0.68) | −0.009 (0.67) |
| FRS | ||
| FRS tertile 1 | ||
| n | 519 | 14,765 |
| RVGRS950 mean (SD) | 0.086 (0.71) | −0.013 (0.67) |
| RVGRS950LDLR- mean (SD) | 0.075 (0.70) | −0.013 (0.67) |
| FRS tertile 2 | ||
| n | 1193 | 14,090 |
| RVGRS950 mean (SD) | 0.046 (0.70) | −0.013 (0.67) |
| RVGRS950LDLR- mean (SD) | 0.039 (0.70) | −0.013 (0.67) |
| FRS tertile 3 | ||
| n | 2131 | 13,152 |
| RVGRS950 mean (SD) | 0.025 (0.67) | 0.0014 (0.68) |
| RVGRS950LDLR− mean (SD) | 0.020 (0.66) | 0.00083 (0.67) |
| Age strata | ||
| Males ≤40 and Females ≤45 | ||
| n | 50 | 42,007 |
| RVGRS950LDLR- mean (SD) | 0.20 (0.76) | −0.0088 (0.67) |
| Males ≤45 and Females ≤50 | ||
| n | 189 | 42,007 |
| RVGRS950LDLR- mean (SD) | 0.13 (0.70) | −0.0088 (0.67) |
| Males ≤50 and Females ≤55 | ||
| n | 536 | 42,007 |
| RVGRS950LDLR- mean (SD) | 0.082 (0.70) | −0.0088 (0.67) |
| Males ≤55 and Females ≤60 | ||
| n | 1128 | 42,007 |
| RVGRS950LDLR- mean (SD) | 0.048 (0.69) | −0.0088 (0.67) |
| ≥2-fold risk for early CADa | ||
| n | 670 | 45,180 |
| RVGRS950LDLR- mean (SD) | 2.00 (0.35) | −0.035 (0.63) |
aCases and controls refer to individuals with ≥2-fold risk and <2-fold risk of early CAD, respectively.