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. 2021 Sep 23;12:742074. doi: 10.3389/fimmu.2021.742074

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Copyright © 2021 Lin, Wang, Zhu, Yu, Wang, Ma, Wang, Yan, Sun and Cheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Phylogenetic tree of vertebrate DDX1. A neighbor-joining phylogenetic tree of vertebrate DDX1 was generated with MegAlign software using DDX1 sequences from the following animals: chickens (NP_989894.1_1), cattle (NP_001068936.1), humans (NP_004930.1), mice (NP_598801.1), pigs (ANR02618.1), baboons (predicted, XP_021780285.1), bats (predicted, XP_023384316.1), cats (predicted, XP_011279621.1), chimpanzees (predicted, XP_001162067.2), dogs (predicted, XP_848865.1), ducks (predicted, XP_027311055.1), finches (predicted, XP_021381054.1), goats (predicted, XP_017911108.1), geese (predicted, XP_013028107.1), horses (predicted, XP_001502097.3), rabbits (predicted, XP_002710081.1), salmon (predicted, XP_014061742.1), and zebrafish (NP_001184253.1). (B) The amino acid sequence homology of different animals. (C) Three-dimensional structure of chDDX1 predicted by Swiss-Mode.