Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 23;12:742074. doi: 10.3389/fimmu.2021.742074

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Lin, Wang, Zhu, Yu, Wang, Ma, Wang, Yan, Sun and Cheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

chDDX1 activated IFN signaling via the chIRF7 pathway. (A) Relative mRNA levels (qRT-PCR) of chIRF7 in DF-1 cells transfected with p3×FLAG-14-chDDX1 or p3×FLAG-14. (B) IRF7 expression (qRT-PCR) in DF-1 cells transfected with RNAi plasmids (shDDX1-1, shDDX1-2, or shNC). (C) chDDX1 expression in IRF7^-/- DF-1 cells (luciferase activity) in IRF7^-/- DF-1 cells and wild-type DF-1 cells transfected with p3×FLAG-14-chDDX1 or p3×FLAG-14 and IFN-β luciferase reporter plasmids. The difference between the experimental and control groups was *p < 0.05 or **p < 0.01.