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. 2021 Sep 23;8:734838. doi: 10.3389/fmed.2021.734838

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Copyright © 2021 Hashimoto, Yoshizaki, Uno, Kitajima, Arai, Tamura, Morishita, Matsuoka, Han, Minamoto, Hirashima, Yamada, Kashiwa, Kameda, Yamaguchi, Tsuchihashi, Iwahashi, Nakayama, Shioda, Nagai and Tanaka.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in SARS-CoV-2 load before and after tocilizumab administration. Viral RNA in the sera of 10 patients with COVID-19 patients before and after tocilizumab administration were quantified by RT-PCR. The red line represents the data of patients requiring mechanical ventilation.