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. 2021 Oct 6;11:19825. doi: 10.1038/s41598-021-98861-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Functional and metabolic heart characteristics. (a) Images show a summary of cardiac viability measurements in control(−) (top row) and MI(−) (bottom row) mice administered the [¹⁸F]-FDG tracer. Note the presence of MI in the apex area in axial, coronal, and sagittal planes (from top to bottom) and a larger size of the post-infarction heart due to its remodelling. (b) Representative PET images in the dorsal and lateral positions. Red arrows show loss of uptake in apex area (c) Comparison of cardiac [¹⁸F]-FDG uptake in a group of control(−), MI(−) and MI(+) mice 7 days after cell implantation into the post-infarction heart and after saline injection. Statistical significance was evaluated with ANOVA and p-values are given as the mean ± SD; *p < 0.05, **p < 0.01.