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. 2021 Oct 6;11:19825. doi: 10.1038/s41598-021-98861-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Metabolic heart activity (viability) measured through glucose uptake. (a) Conversion of PET images to maps of radiotracer activity in the heart (left) and their counterparts presented as polar maps for MI( +) mice (right). A reduction in the metabolically inactive zone can be seen in the walls and apex segments. (b) Scheme of the polar map by 17 AHA segmentation with indication of septum, anterior and lateral directions. (c) Graph for dual cardiac viability PET imaging in control(−) and MI( +).