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. 2021 Oct 6;11:19839. doi: 10.1038/s41598-021-99399-2

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Performance of drug rankings reported in literature for COVID-19 drug repurposing. The (a,b) panels show the absolute values of RHR and precision 20, respectively. The (c,d) show the $- l o g_{10} (p value)$ of the RHR and precision 20, respectively. The dotted red line indicates the 0.05 significance threshold. The analyses have been performed using only FDA-approved drugs (green bars) and without any FDA filtering (red bars). The plot has been generated by the ggplot2⁸¹ R package.