Table 3.
Hospitalisations (WHO score >= 4) by SARS-CoV-2 lineage and WHO clinical progression score.
| ChAdOx1 nCoV-19 | Control | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| WHO clinical progression score | 4 | 5 | 6 | 10 | 4 | 5 | 6 | 10 | |
|
Secondary cases (>21 days after dose 1, <15 days after dose 2) |
Undetermined/no swab | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 1 |
| B.1.1.33 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |
| P.1 (Gamma) | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | |
| Total | 0 | 6 | |||||||
|
Primary cases > =15 days after dose 2 |
Undetermined/no swab | 0 | 1 | 0 | 0 | 3 | 3 | 4 | 1 |
| B.1.1.28 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | |
| P.1 (Gamma) | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | |
| P.2 (Zeta) | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | |
| Total | 1 | 18 | |||||||
| VE 95% (95% CI 61%, 99%) | |||||||||
*Undetermined lineage are those where a lineage could not be assigned due to low viral load or degraded RNA.
4 = Hospitalised; no oxygen therapy, 5 = Hospitalised; oxygen by mask or nasal prongs, 6 = Hospitalised; oxygen by NIV or high flow, 10 = dead.