Table 2.
Comparison of immunological marker and inflammation parameter levels and NRS scores of patients before and after treatment
| Immunological markers and inflammation parameter levels | Before treatment (n = 40) | After treatment (n = 40) | P value |
|---|---|---|---|
| CD3+, CD4+ T cells% | 30.28 ± 12.27 | 34.93 ± 11.70 | 0.028* |
| CD4+, PD1+, CXCR5+ T cells% (Tfh) | 2.61 ± 0.96 | 2.59 ± 2.25 | 0.208 |
| CD4+, CXCR3+ T cells% (Th1) | 28.32 ± 11.29 | 25.20 ± 11.92 | 0.091 |
| CD4+, CCR6+ T cells% (Th17) | 9.41 ± 5.44 | 10.24 ± 6.14 | 0.834 |
| CD4+, FOXP3+ T cells% (Treg) | 5.59 ± 2.56 | 5.56 ± 1.98 | 0.957 |
| CD4+, CD25+ T cells% (Treg) | 6.02 ± 2.77 | 5.63 ± 2.04 | 0.476 |
| CD4+, IFN-γ+ T cells% (Th1) | 23.05 ± 18.80 | 20.09 ± 15.05 | 0.426 |
| CD4+, IL-17A+ T cells% (Th17) | 4.75 ± 5.02 | 5.80 ± 3.13 | 0.036* |
| CD4+, IL-4+ T cells% (Th2) | 4.33 ± 3.64 | 3.44 ± 2.73 | 0.261 |
| ESR (mm/hr) | 19.54 ± 11.57 | 9.83 ± 7.77 | 0.001* |
| CRP (mg/L) | 8.44 ± 9.32 | 3.00 ± 3.61 | 0.001* |
| NRS | 8.00 ± 0.88 | 3.00 ± 0.84 | 0.001* |
Values are presented as mean ± standard deviation.
Tfh: T follicular helper cells, ESR: erythrocyte sedimentation rate, CRP: C-reactive protein, NRS: numeric rating scale.
*P < 0.05, significant.