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. 2021 Sep 23;11:683695. doi: 10.3389/fonc.2021.683695

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Copyright © 2021 Xu, Lu, Luo, Wang, Zhang, Cao and Jiao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DSF enhances the radiosensitivity of pancreatic cells in vivo. PANC-1 xenograft mice were divided into 4 groups (n=5): (1) intraperitoneal injection of vehicle (negative control); (2) intraperitoneal injection of DSF (75 mg/kg); (3) combination of vehicle and irradiation (5 Gy X-rays); and (4) combination of DSF and irradiation. (A) The tumor value was measured each day and calculated with the formula V=1/2ab² (a=length, b=width). *p < 0.05, ****p < 0.0001, using two-way ANOVA. (B) The weight of the mice was measured daily. (C) Visual observation of tumors in each group. (D) HE staining of tumor tissue.