Fig. 5.

PHYLIP Phylogenetic tree of the synuclein and 14-3-3 proteins families. The phylogenetic tree shows the unrooted relative relatedness among the synucleins and seven 14-3-3 human isoforms according to the alignment illustrated in Fig. 1. Each branch is labeled according to the protein name for the synucleins and the RCSB PDB ID and protein name for the 14-3-3 proteins. The 14-3-3 labels are as follows: 14-3-3 sigma: “1YZ5_1433s”, 14-3-3 epsilon: “3UAL_1433p”, 14-3-3 eta: “2C74_1433e”, 14-3-3 gamma: “6GKG_1433g”, 14-3-3 theta/tau: “5IQP_1433t”, 14-3-3 zeta/delta: “6EF5_1433z”, 14-3-3 beta: “5N10_1433b”.