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. 2021 Sep 23;54:101328. doi: 10.1016/j.molmet.2021.101328

Figure 4.

Figure 4

De novo adipogenesis contributes more to iWAT expansion in HFD-fed male mice. (A) Correlation between the weights of the WAT depots (gWAT and iWAT) as % BW and % de novo adipogenesis (hyperplasia) in KI/td male mice fed either NC or HFD for 8 weeks. Mice were started on HFD at 9 weeks of age and euthanized at 17 weeks. Each point indicates an individual mouse (NC, n = 6; HFD, n = 10). (B) Correlation between the weights of the WAT depots (gWAT and iWAT) as % BW and % de novo adipogenesis (hyperplasia) in KI/td female mice fed either NC or HFD for 8 weeks. Mice were started on HFD at 9 weeks of age and euthanized at 17 weeks. Each point indicates an individual mouse (NC, n = 6; HFD, n = 7).