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. 2021 Sep 23;9:745637. doi: 10.3389/fcell.2021.745637

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Copyright © 2021 Klaas, Mäemets-Allas, Heinmäe, Lagus, Cárdenas-León, Arak, Eller, Kingo, Kankuri and Jaks.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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THBS4 is a soluble dermal inflammatory signal that activates the fibroblast migration for skin regeneration and wound healing. See section “Discussion” for closer explanation.