TABLE 2.
Sensitivity of cervical cytology for endometrial cancer detection among 371 women, stratified by clinico‐pathological characteristics
|
Clinico‐pathological variables N = 371 |
Cervical cytology results | p value b | |
|---|---|---|---|
|
Normal N (%) |
Abnormal a N (%) |
||
| Histology | |||
| Endometrioid | 212 (78.8%) | 57 (21.2%) | .002 |
| Non‐endometrioid | 64 (62.8%) | 38 (37.3%) | |
| Grade | |||
| Grade 1 | 134 (88.1%) | 18 (11.8%) | <.001 |
| Grade 2 | 33 (67.3%) | 16 (32.7%) | |
| Grade 3 | 76 (65.5%) | 40 (34.8%) | |
| Stage c | |||
| I | 93 (83.8%) | 18 (16.2%) | <.001 b |
| II/III/IV | 18 (45.0%) | 22 (55.0%) | |
| Tumour extent | |||
| T1 | 218 (83.9%) | 42 (16.2%) | <.001 b |
| T2 | 8 (32.0%) | 17 (68.0%) | |
| T3 | 29 (61.7%) | 18 (38.3%) | |
| Lymphatic affection (node) | |||
| N0 | 183 (79.2%) | 48 (20.8%) | .007 |
| N1 and N2 | 18 (56.3%) | 14 (43.8%) | |
| Time period of diagnosis | |||
| 1990–2009 | 95 (75.4%) | 31 (24.6%) | .895 |
| 2010–2017 | 66 (75.0%) | 22 (25.0%) | |
| 2018–2020 | 105 (72.9%) | 39 (27.1%) | |
| Time lag between cervical cytology and hysterectomy | |||
| ≤2 months | 145 (68.4%) | 67 (31.6%) | .003 |
| >2 months | 131 (82.4%) | 28 (17.6%) | |
Numbers do not always add up due to missing data.
Abbreviation: IQR, inter‐quartile range.
a
Abnormal Pap results include squamous lesions, atypical glandular cells of undetermined significance (AGUS), atypia and malignant lesions.
b
Fisher's exact test.
c
Data available only for the prospective study.