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Histological and immunohistochemical features of classic Hodgkin lymphoma (CHL)‐type methotrexate (MTX)‐associated lymphoproliferative disorder (LPD). (A) Hodgkin and Reed–Sternberg (HRS) cells proliferate on a background containing extensive non‐neoplastic immune cells (HE ×400). (B) The HRS cells are CD30‐positive (×400) and (C) EBER‐positive (×400). (D) Most of the CHL‐type MTX‐associated LPDs stain positive for PD‐L1 (×400)
