TABLE 2.

Urinary biomarkers values according to the presence of acute kidney injury in patients hospitalized in wards and receiving vancomycin.

Urinary biomarker	Non-AKI n = 71	AKI n = 23	p
IL-18 (pg/ml)
0–48 h	203.14 ± 119.27	260.45 ± 191.44	0.62
48–96 h	156.55 ± 89.8	167 ± 118.12	0.87
96–144 h	360.5 ± 20.,7	191 ± 147.8	0.7
144–192 h	98.68 ± 52.54	256.7 ± 160.11	0.027
KIM-1 (ng/ml)
0–48 h	1.2 ± 0.13	1.3 ± 0.14	0.77
48–96 h	0.99 ± 0.22	1.1 ± 0.26	0.58
96–144 h	0.99 ± 0.23	1.8 ± 0.73	0.005
144–192 h	0.94 ± 0.1	1.05 ± 0.21	0.76
NGAL (ng/ml)
0–48 h	262.2 ± 58.7	512.1 ± 86.1	0.09
48–96 h	229.1 ± 68.1	551.9 ± 71.9	0.03
96–144 h	374.7 ± 73.1	818.7 ± 99.8	0.03
144–192 h	252.9 ± 49.3	679.2 ± 91.5	0.012
TIMP-2 x IGFBP-7/1,000 (ng/ml)
0–48 h	0.72 (0.18–5.01)	0.76 (0.28–5.18)	0.71
48–96 h	1.62 (0.61–5.61)	1.75 (0.07–4.46)	0.63
96–144 h	0.98 (0.48–6.30)	0.94 (0.58–5.92)	0.43
144–192 h	1.77 (0.60–4.46)	1.66 (0.082–4.09)	0.16

IL-18, interleukin 18; KIM-1, kidney injury molecule-1; NGAL, neutrophil gelatinase-associated lipocalin; TIMP-2, tissue inhibitor of metalloproteinases 2; IGFBP-7, insulin-like growth factor binding protein 7.