Table 8.

Effects of environmental conditions and cellulose levels on pro-inflammatory cytokines and lipid mediators for weaned pig for 14 days after weaning

Item	Feeding regimen						SEM	p-value1)
	Good sanitary			Poor sanitary
	Cellulose 0%	Cellulose 1%	Cellulose 2%	Cellulose 0%	Cellulose 1%	Cellulose 2%		E2)	D2)	E×D2)
d 7 (pg/mL)
IL-1β	0.00	0.00	0.00	0.00	12.00	0.00	1.262	NS	NS	NS
TNF-α	9.66	0.97	2.68	26.35	18.24	9.23	3.637	†	NS	NS
COX-2	109.81b	100.78c	84.00d	133.70a	116.80b	99.13c	3.209	*	*	NS
PGE2	6.60	12.56	12.82	36.19	67.52	28.38	5.022	*	NS	NS
LTB4	452.77	307.70	90.79	785.46	567.55	160.91	66.402	NS	NS	NS
d 14 (pg/mL)
IL-1β	0.00	0.00	0.00	0.00	67.69	0.00	7.574	NS	NS	NS
TNF-α	6.34	5.01	5.86	25.23	18.83	7.94	2.857	†	NS	NS
COX-2	116.08	98.56	107.85	141.62	133.29	117.38	5.041	*	NS	NS
PGE2	8.17	27.19	37.59	103.01	55.78	70.79	7.977	*	NS	NS
LTB4	277.06	218.54	201.13	417.64	375.02	175.56	64.075	NS	NS	NS

SEM, pooled standard error of mean; IL-1β, interleukin 1β; TNF-α, tumor necrosis factor α; COX-2, cyclooxygenase-2; PGE₂, prostaglandin E₂; LTB₄, leukotriene B₄.

¹⁾Significance level: NS, no significance;

^†p<0.10,

^*p<0.05.

²⁾E, environmental conditions (good sanitary vs poor sanitary); D, dietary treatments; E×D, interaction between environmental conditions and dietary treatments.

^a–dMeans in the same row with different superscripts differ in D (p<0.05).