Table 1.
Comparison of clinical characteristics of 239 COVID-19 patients in general and severe/critical group
| Overall (n=239) | Ordinary group (n=176) | Severe/critical group (n=63) | p value | |
|---|---|---|---|---|
| Age (x±s) | 48.1±17.6 | 43.9±14.5 | 59.8 ±14.1 | < 0.001 |
| Gender (n, %) | ||||
| Female (n, %) | 107 (44.7) | 90 (50.9) | 16(25) | 0.032 |
| Male (n, %) | 132 (55.3) | 86 (49.1) | 47(75) | |
| Close contact with confirmed cases (n, %) | 194(81) | 144 (81.8) | 50 (79.2) | 0.972 |
| Comorbidities (n, %) | ||||
| Hypertension (n, %) | 48 (20.3) | 16 (9.1) | 32 (50.8) | < 0.001 |
| Diabetes (n, %) | 35 (14.5) | 13 (7.3) | 22 (34.9) | 0.386 |
| Cerebrovascular disease (n, %) | 9 (3.8) | 0 | 9 (14.3) | 0.026 |
| Chronic kidney disease (n, %) | 9 (3.8) | 6 (3.6) | 3 (4.8) | ＞0.99 |
| Chronic liver disease (n, %) | 9 (3.8) | 9 (5.5) | 0 | 0.549 |
| Coronary heart disease (n, %) | 9 (3.8) | 3 (1.8) | 6 (9.5) | 0.218 |
| Malignant tumor (n, %) | 3 (1.3) | 3 (1.8) | 0 | ＞0.99 |
| Immunosuppressive (n, %) | 3 (1.3) | 3 (1.8) | 0 | ＞0.99 |
| COPD (n, %) | 23 (9.6) | 7 (3.9) | 16 (25.4) | < 0.001 |
| No comorbidity (n, %) | 157 (65.8) | 14 1(80) | 16(25.4) | < 0.001 |
| 1 comorbidity (n, %) | 58 (24.1) | 19 (10.9) | 39(61.9) | |
| 2 comorbidities (n, %) | 15 (6.3) | 13 (7.3) | 2(3.2) | |
| ≥3 comorbidities (n, %) | 9 (3.8) | 3 (1.8) | 6(9.5) | |
| Symptoms (n, %) | ||||
| Fever≥37.3℃ (n, %) | 203 (84.8) | 147 (83.6) | 56 (88.9) | 0.921 |
| Dry cough (n, %) | 136(57) | 99 (56.4) | 37 (58.7) | 0.871 |
| Fatigue, muscle aches (n, %) | 73 (30.4) | 54 (30.9) | 19 (30.9) | 0.877 |
| Dyspnea (n, %) | 27 (11.4) | 1 6(9.1) | 11 (17.5) | 0.555 |
| Expectorant (n, %) | 30 (12.7) | 22 (12.7) | 8 (12.7) | 0.734 |
| Dizziness, headache (n, %) | 18 (7.6) | 6 (3.6) | 12 (19.0) | 0.121 |
| Poor appetite (n, %) | 1 5(6.3) | 10 (5.5) | 5 (7.9) | 0.985 |
| Sore throat (n, %) | 9 (3.8) | 3 (1.8) | 6 (9.5) | 0.218 |
| Diarrhea (n, %) | 12 (5.1) | 3 (1.8) | 9 (14.3) | 0.152 |
| Vomiting (n, %) | 23 (9.6) | 12 (6.8) | 11 (17.5) | 0.831 |
| Stomachache (n, %) | 23 (9.6) | 12 (6.8) | 11 (17.5) | 0.831 |
| Onset of symptom to hospital admission | 5 (4~8) | 5 (4~7) | 6.5 (4~10) | 0.018 |
| Signs [median (IQR)] | ||||
| Pulse [median (IQR)] | 85 (79~92) | 86 (80~92) | 82 (74~93) | 0.096 |
| Respiratory rate [median (IQR)] | 20 (19~20) | 20 (19~20) | 20 (18~20) | 0.368 |
| Systolic pressure (x±s) | 124.8±13.2 | 121.2±9.5 | 133.3±16.5 | < 0.001 |
| Diastolic pressure (x±s) | 77.0±11.0 | 74.2±9.5 | 83.3±11.7 | < 0.001 |
| Blood oxygen saturation [median (IQR)] | 97(93~98) | 97(96~98) | 91(89~93) | < 0.001 |